Serophene® (clomiphene citrate tablets USP)

Serophene® is an oral prescription brand of clomiphene citrate. Serophene® is commonly prescribed as an initial treatment by an Obstetrician / Gynecologist (OB/GYN) or a Fertility Specialist, also called a Reproductive Endocrinologist (RE). It is prescribed for the treatment of ovulatory failure in female patients who wish to conceive.

Why Serophene® is used.

Clomiphene citrate is an initial treatment. It works by initiating the release of gonadotropin releasing hormone (GnRH) from the hypothalamus. This causes the pituitary gland to release more follicle stimulating hormone (FSH) and luteinizing hormone (LH) to stimulate follicle development and ovulation. Learn more about how clomiphene citrate works. Also learn for how many cycles Serophene® should be used.

Ask your healthcare provider if Serophene® is right for you.

If you have questions about Serophene® or any other EMD Serono product, call Fertility LifeLines™ at 1-866-LETS-TRY (1-866-538-7879). All calls are free and confidential.

Important Safety Information

Serophene® should only be prescribed by doctors specializing in infertility or reproductive health. Serophene® can cause serious side effects including, visual symptoms such as spots or flashes, ovarian hyperstimulation syndrome (OHSS), with or without blood vessel and lung complications, and multiple births. Serophene® should not be used in women who are allergic to clomiphene citrate preparations or their ingredients, who have liver disease, who have abnormal bleeding from the uterus, have ovarian cysts or enlarged ovaries, have uncontrolled thyroid or adrenal problems, have have a pituitary tumor or other tumor in the brain or who are pregnant. Prolonged use of Serophene® may increase the risk of ovarian cancer. The most common side effects in patients using Serophene® include hot flashes, stomach discomfort and bloating, nausea and vomiting, breast discomfort, visual symptoms, headache and vaginal bleeding. Please see the Full Prescribing Information and FAQ's for more information.