Ovidrel® PreFilled Syringe (choriogonadotropin alfa injection)

Ovidrel® PreFilled Syringe is the first and only recombinant human chorionic gonadotropin (r–hCG) approved in the world. Ovidrel® PreFilled Syringe is available in a ready–to–inject, prefilled syringe, eliminating the need for reconstituting.

The Ovidrel® PreFilled Syringe is manufactured to the highest standards of purity using recombinant human DNA technology. Ovidrel® PreFilled Syringe is the only hCG available for subcutaneous (just under the skin) injection in the United States. Other hCG products available in the U.S. are extracted from human urine and may require deeper, intramuscular injections.

Why Ovidrel® PreFilled Syringe is used.

Ovidrel® PreFilled Syringe is used in fertility treatment cycles to help follicles mature and to trigger the release of mature eggs from a woman's ovaries following treatment with products containing human follicle stimulating hormone, for example, Gonal–f® (follitropin alfa for injection).

Ask your healthcare provider if Ovidrel® PreFilled Syringe is right for you.

• Ovidrel® PreFilled Syringe Instructions for Use

If you have questions about Ovidrel® PreFilled Syringe or any other EMD Serono fertility product, call Fertility LifeLines™ at 1–866–LETS-TRY (1-866-538-7879). All calls are free and confidential.

EMD Serono fertility products in the infertility treatment cycle

Important Safety Information

Ovidrel® PreFilled Syringe should only be prescribed by doctors specializing in infertility or reproductive health. Ovidrel® PreFilled Syringe can cause serious side effects including, ovarian hyperstimulation syndrome (OHSS), with or without blood vessel and lung problems, and multiple births. Ovidrel® PreFilled Syringe should not be used in women who, are allergic to hCG products, have ovaries that no longer make eggs, have uncontrolled thyroid or adrenal problems, have cancer in their female organs, have a pituitary tumor or other tumor in their brain, have abnormal bleeding from the uterus or vagina or are pregnant or think they may be pregnant. Women who are nursing should not use Ovidrel® PreFilled Syringe. The most common side effects in women using Ovidrel® PreFilled Syringe include stomach pain, injection site reactions, upset stomach, and vomiting. Please see the Full Prescribing Information and FAQ's for more information.