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Fertility Treatments

Fertility Medications

Cetrotide® (cetrorelix acetate for injection) 0.25 mg and 3 mg

Below is some helpful information about Cetrotide® (cetrorelix acetate for injection) 0.25 mg and 3 mg.

You should also read the patient information leaflet contained in your medication box and ask your doctor, nurse, or pharmacist to explain anything you do not understand.

What is Cetrotide®?

Cetrotide® (cetrorelix acetate for injection) blocks the effects of a natural hormone, called gonadotropin-releasing hormone (GnRH). GnRH controls the secretion of another hormone, called luteinizing hormone (LH), which induces ovulation during the menstrual cycle.

During hormone treatment for ovarian stimulation, premature ovulation may lead to eggs that are not suitable for fertilization. Cetrotide® blocks such undesirable premature ovulation.

What are the uses of Cetrotide®?

Cetrotide® (cetrorelix acetate for injection) is used to prevent premature ovulation during controlled ovarian stimulation.

Who should not use Cetrotide®?

Do not use Cetrotide® (cetrorelix acetate for injection) if you:

  • Have severe kidney disease
  • Are allergic to cetrorelix acetate, mannitol or exogenous peptide hormones (medicines similar to Cetrotide®)
  • Are pregnant, or think that you might be pregnant, or if you are breastfeeding.
  • Consult your doctor before taking Cetrotide® if you have had severe allergic reactions.
What are the possible side effects of Cetrotide®?

Your doctor or staff member should review with you the risks and benefits of using Cetrotide® (cetrorelix acetate for injection). As with any medication, report any and all side effects, symptoms, or physical changes to your doctor.

Mild and short lasting reactions may occur at the injection site like reddening, itching, and swelling. Nausea and headache have also been reported.

Call your doctor if you have any other side effect or if you are unsure about the effect of this medicine.

IMPORTANT

Contact your doctor in case of overdosage immediately to check whether an adjustment of the further ovarian stimulation procedure is required.

If you suspect that you may have taken more than the prescribed dose of this medicine, contact your doctor immediately. This medicine was prescribed for your particular condition. Do not use it for another condition or give the drug to others.
How should I use Cetrotide®?

You may self-inject Cetrotide® (cetrorelix acetate for injection) after special instruction from your doctor.

To fully benefit from Cetrotide®, please read carefully and follow the instructions given below, unless your doctor advises you otherwise.

Ovarian stimulation therapy is started on cycle Day 2 or 3. Cetrotide® is injected under the skin either once daily (0.25 mg dose) or once (3 mg dose), as directed by your physician. When an ultrasound examination shows that you are ready, another drug (hCG) is injected to induce ovulation.

Cetrotide® is for injection under the skin of the lower abdominal area, preferably around, but staying at least one inch away from the belly button. If you are on a multiple dose (0.25 mg) regimen, choose a different injection site each day to minimize local irritation.

Dissolve Cetrotide® powder only with the water contained in the pre-filled syringe. Do not use a Cetrotide® solution if it contains particles or if it is not clear.

Before you inject Cetrotide® yourself, please carefully read the instructions included in the packet with the needles and pre-filled syringe.

Watch this brief video that demonstrates how to administer Cetrotide®.

What should I do if forget to take Cetrotide®?

Do NOT take a double dose of Cetrotide® (cetrorelix acetate for injection). Contact your doctor if you forget to take a dose of Cetrotide®.

Can I take Cetrotide® with any other medication?

Inform your doctor and pharmacist if you are taking or have taken any other medicines, even those not requiring a prescription.

Storing Cetrotide®

Store Cetrotide® (cetrorelix acetate for injection) in a cool dry place protected from excess moisture and heat.

Store Cetrotide® 3 mg at 25°C (77°F). Excursions are permitted to 15 - 30ºC (59 - 86ºF).

Store Cetrotide® 0.25 mg in the refrigerator at 2 - 8°C (36 - 46°F). Keep the packaged tray in the outer carton in order to protect it from light.

Do not use Cetrotide® powder or the pre-filled syringe after the expiration date, which is printed on the labels and on the carton, and dispose of the vial and the syringe properly.

The solution should be used immediately after preparation.

Store the medicine out of the reach of children.

Download Full Prescribing Information for Cetrotide®

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Where can I find more information about Cetrotide®

This information on this website is a summary of the important patient information about Cetrotide® (cetrorelix acetate for injection). If you have any questions or problems, talk to your doctor or other health care provider.

Cetrotide® is manufactured and distributed by EMD Serono, Inc. You can contact EMD Serono at 1-866-538-7879.

 

IMPORTANT INFORMATION ABOUT THE PROPER USE AND RISKS OF CETROTIDE® (cetrorelix acetate for injection):

What are the uses of Cetrotide® (cetrorelix acetate for injection)?

Cetrotide® blocks the effects of a natural hormone, called gonadotropin-releasing hormone (GnRH). GnRH controls the secretion of another hormone, called luteinizing hormone (LH), which induces ovulation during the menstrual cycle.

During hormone treatment for ovarian stimulation, premature ovulation may lead to eggs that are not suitable for fertilization. Cetrotide® blocks such undesirable premature ovulation.

Who should not use Cetrotide®?

Cetrotide® should not be used in patients who are pregnant, think they might be pregnant, or are breastfeeding.

Cetrotide® should not be used in patients with kidney disease.

Patients that are allergic to cetrorelix acetate, mannitol, or exogenous peptide hormones (medicines similar to Cetrotide®) should not use Cetrotide®. Consult your doctor before taking Cetrotide® if you have had severe allergic reactions.

What are the possible side effects of Cetrotide®?

Your doctor should review with you the risks and benefits of using Cetrotide®. As with any medication, report any and all side effects, symptoms, or physical changes to your doctor.

Mild and short-lasting reactions may occur at the injection site like reddening, itching, and swelling. Nausea and headache have also been reported.

Call your doctor if you have any other side effect or if you are unsure about the effect of this medicine.

© 2013 EMD Serono, Inc. and its affiliates.

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